| 产品详情 |
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| Product Name | TP-434 |
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| Description | A fluorocycline antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria (MICs = 0.03-0.25 and 0.125-0.25 µg/ml for S. aureus and Enterobacteriaceae clinical isolates, respectively); active against a wide range of bacteria except for P. aeruginosa and B. cenocepacia (MIC90s = 50 = 0.22 µM); maintains antibacterial activity against E. coli expressing tetracycline resistance genes comparable to a lacZ control (MICs = 0.031 - 4 and 0.063 µg/mL, respectively); protective against tetracycline resistant S. aureus, MRSA, S. pyogenes, and E. coli in a mouse septicemia model (PD50s = 0.3, 0.3-1, 1, and 1.2-4.4 mg/kg, respectively); reduces the number of CFUs of S. pneumoniae tet(M) in a mouse lung infection model (3-12 mg/kg, i.v.) |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Eravacycline |
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| Gene, Accession, CAS # | CAS: 1207283-85-9 |
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| Catalog # | 24059-10 |
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| Price | |
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| Order / More Info | TP-434 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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| 产品资料 |
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