| 产品详情 |
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| Antigenic Specificity | PTPN22 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100ug (sample available) |
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| Concentration | 0.5-1mg/ml, actual concentration varies by lot. |
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| Applications | ELISA, IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit IgG polyclonal Picoband™ antibody for PTPN22 detection. Tested with WB, IHC-P, Direct ELISA in Mouse;Rat. No cross reactivity with other proteins. Protein tyrosine phosphatase, non-receptor type 22 (lymphoid), also known as PTPN22, is a protein that in humans is encoded by the PTPN22 gene. This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
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| Immunogen | E. coli-derived mouse PTPN22 recombinant protein (Position: M1-Q309). |
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| Other Names | Tyrosine-protein phosphatase non-receptor type 22; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; PEST-domain phosphatase; PEP; Ptpn22; Ptpn8 |
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| Gene, Accession # | Ptpn22, UniProt: P29352 |
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| Catalog # | A00581-1 |
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| Price | |
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| Order / More Info | PTPN22 Antibody from BOSTER BIO |
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| Product Specific References | n/a |
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