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| Product Name | PAPC |
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| Description | MW: 19,194 Da. Product Description: 1-palmitoyl-2-arachidonoyl-sn-phosphatidylcholine (PAPC), is a naturally occuring phospholipid containing polyunsaturated arachidonic acid, which is a common lipid in mammalian cell membranes and lipoproteins. PAPC can be used as an unoxidized control in experiments utilizing oxidized PAPC (OxPAPC; cat. # HC4035/HC4036). OxPAPC, is a prototypic biologically active oxidized phospholipid first isolated from LDL minimally modified by oxidation (MM-LDL). Ox |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | Application Use: 1. For use of total amount in once: Add buffer or medium used in the experiment and resuspend lipids by vigorous vortexing for at least 30 seconds. Optimal working concentrations are up to 100 ug/ml. Do not exceed concentrations of 0.5 mg/ml since PAPC is poorly soluble in water. Sonicate if necessary to ensure better resuspension of PAPC. PAPC is used as negative control for OxPAPC. The concentration range in which PAPC can be used is dependent on the cell type and should be equal to OxPAPC, usually below 100 ug/ml. Please note that PAPC can be oxidized by cells. |
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| Other Names | [PapC; PedC; PapC; PedC] |
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| Gene, Accession, CAS # | PAPC, Gene ID: 1090331, Accession: NP_857604.1 |
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| Catalog # | MBS584644 |
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| Order / More Info | PAPC from MYBIOSOURCE INC. |
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| Product Specific References | 1. Birukov, K et al; Signal transduction pathways activated in human pulmonary endothelial cells by OxPAPC, a bioactive component of oxidized lipoproteins. Microvasc Res 2004, 67: 18 2. Zheng, M et al; Inhibition of LPS- and CpG DNA-induced TNF-alpha response by oxidized phospholipids. Am J Physiol Lung Cell Mol Physiol 2004, 286: L808 3. Birukov, K et al; Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac. Circ Res 2004, 95: 892 4. Furnk |
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