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| Product Name | PAPC, Oxidized (OxPAPC, Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine) |
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| Description | Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (OxPAPC) is a prototypic biologically active oxidized phospholipid first isolated from LDL minimally modified by oxidation (MM-LDL). OxPAPC is an active principle of MM-LDL that mimics several pro- and anti-inflammatory effects induced by oxidized lipoproteins. Oxidation of PAPC generates a mixture of oxidized phospholipids containing either fragmented or full- length oxygenated sn-2 residues. The best-characterized oxidatively fragmented species contain a five- carbon sn-2 residue bearing omega-aldehyde or omega-carboxyl groups. Oxydation of arachidonic acid residue also produces phospholipids containing esterified isoprostanes. Both fragmented and full-length oxygenated species can regulate immune reactions. Pro-inflammatory effects of OxPAPC include stimulation of endothelial cells to bind monocytes and induction of tissue clotting factor, IL-8, MCP-1, G-CSF and other mediators of atherothrombosis. Anti- inflammatory ef |
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| Size | 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P3100-31 |
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| Order / More Info | PAPC, Oxidized (OxPAPC, Oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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