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| Product Name | RYR1, Recombinant, Human, aa1-534, His-Tag (Ryanodine Receptor 1) |
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| Description | Purity ~90% (SDS-PAGE). Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis. Source: Recombinant protein corresponding to aa1-534 from RYR1, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~63.3kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Skeletal muscle calcium release channel, Skeletal muscle ryanodine receptor, Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor, RYR1, RYDR |
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| Gene, Accession, CAS # | SwissProt: P21817 |
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| Catalog # | 375170 |
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| Order / More Info | RYR1, Recombinant, Human, aa1-534, His-Tag (Ryanodine Receptor 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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