| 产品详情 |
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| Product Name | RAB1A, Recombinant, Human, aa2-205, GST-Tag (Ras-related Protein Rab-1A, YPT1-related Protein) |
| Description | Purity ~85% (SDS-PAGE). The small GTPases Rab are key regulators of intracellular mbrane trafficking, from the formation of transport vesicles to their fusion with mbranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to mbranes different sets of downstream effectors directly responsible for vesicle formation, movent, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assbly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport. Source: Recombinant protein corresponding to aa2-205 from human RAB1A, fused to GS |
| Size | 50ug, 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | SwissProt: P62820 |
| Catalog # | 370775 |
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| Order / More Info | RAB1A, Recombinant, Human, aa2-205, GST-Tag (Ras-related Protein Rab-1A, YPT1-related Protein) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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