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| Product Name | SRC1 |
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| Description | Highly Purified. Peptide is used to block SRC-1 Rabbit mAb reactivity in immunohistochemistry protocols. There are three members of the steroid receptor co-activator (SRC) family of proteins: SRC-1 (NCoA1), SRC-2 (TIF2/GRIP1/NCoA-2) and SRC-3 (ACTR/pCIP/ RAC3/TRAM-1/AIB1). The SRC family members all share significant structural homology and function in a similar fashion to stimulate transcription mediated by nuclear hormone receptors and other transcriptional activators such as STAT3, NF-κB, E2F1 and p53 (1-4). Two SRC proteins, SRC-1 and SRC-3, function as histone acetyltransferases (5,6). In addition, all three family members can recruit other histone acetyltransferases (CBP/p300, PCAF) and histone methyltransferases (PRMT1, CARM1) to target promoters and cooperate to enhance expression of many genes (5-8). The SRC proteins play important roles in multiple physiological processes including cell proliferation, cell survival, somatic cell growth, mammary gland development, female |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | IHC N |
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| Other Names | SRC1 (Steroid Receptor Coactivator 1, NCOA1, Nuclear Receptor Coactivator 1, NCoA-1, F-SRC-1) Blocking Peptide |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | S6505-02A |
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| Price | |
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| Order / More Info | SRC1 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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