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| Product Name | Catenin beta Recombinant protein |
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| Description | MW: ~115kDa. Recombinant full-length human Catenin beta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: beta-catenins are cytoplasmic proteins that are ubiquitously expressed. These proteins associate with E-cadherin at cellular junctions (1). beta-catenin interacts with TCF and LEF transcription factors and is an essential member of the Wingless-Wnt signal transduction pathway. The adenomatous polyposis coli (APC) tumor-suppress |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [CTNNB; FLJ25606; Catenin b Protein] |
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| Gene, Accession, CAS # | CTNNB1; CTNNB1; CTNNB; MRD19; armadillo; CTNNB, Gene ID: 1499, Accession: NP_001895.1 |
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| Catalog # | MBS515157 |
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| Order / More Info | Catenin beta Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Morin, P.J. et al: Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997; 275(5307):1787-1790. 2. Liu, J. et al: Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein. Mol. Cell. 2001;7(5):927-36. |
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