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| Product Name | Furin, Recombinant Mouse |
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| Description | Purity ~95% (SDS-PAGE). Furin is a member of the proprotein convertase (PC) family, which belongs to the subtilisin superfamily of serine proteases. As a cellular protease, Furin processes a variety of proproteins in secretory pathway compartments by cleaving after ArgXaaLys/ArgArglike motifs, which usually reside at the end of the pro regions of these proproteins. Examples of the proprotein substrates are growth factors and receptors, extracellular matrix proteins, and other proteases. Furin has an essential role in embryogenesis and homeostasis and is implicated in various pathologies such as cancer, neurodegenerative diseases and anthrax (1, 2). Mouse Furin is a 793 amino acid type I transmembrane protein precursor with a signal peptide (residues 1 24), a pro region (residues 25 107), which play a crucial role in the folding, activation and transport of Furin, and a mature chain (residues 108 793) (2, 3). Mouse Furin displays ~94% homology to the human Furin sequence and >99% homolo |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P23188 |
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| Catalog # | F9201-20 |
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| Price | |
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| Order / More Info | Furin, Recombinant Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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