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| Product Name | Plasminogen (Pg) BioAssay™ ELISA Kit (Antibodies only) |
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| Description | Plasminogen (Pg) is synthesized in the liver and circulates in plasma at a concentration of ~200ug/ml (~2.3uM). Plasminogen is a single-chain glycoprotein of ~88kD that consists of a catalytic domain followed by five kringle structures. Within these kringle structures are four low-affinity lysine binding sites and one high- affinity lysine binding site. It is through these lysine binding sites that plasminogen binds to fibrin and to alpha-2antiplasmin. Native plasminogen (glu-plasminogen) exists in two variants that differ in their extent of glycosylation, and each variant has up to six isoelectric forms with respect to sialic acid content, for a total of 12 molecular forms. Activation of glu-plasminogen by the plasminogen activators urokinase (UPA), or tissue plasminogen activator (tPA) occurs by cleavage after residue Arg560 to produce the two-chain active serine protease plasmin. In a positive feedback reaction, the plasmin generated cleaves an ~8kD peptide from glu- plasminogen, pr |
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| Size | 1 kit |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P4256-49 |
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| Order / More Info | Plasminogen (Pg) BioAssay™ ELISA Kit (Antibodies only) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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