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| Product Name | Recombinant Zaire ebolavirus (strain Kikwit-95) (ZEBOV) (Zaire Ebola virus) Envelope glycoprotein |
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| Description | 33-501aa; Extracellular Domain. MW: 54.98kd. Purity >90% as determined by SDS-PAGE. GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only fa |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [GP1,2; GP; Cleaved into the following 3 chains: GP1; GP2; GP2-delta] |
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| Gene, Accession, CAS # | GP, Accession: P87666.1 |
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| Catalog # | MBS1107736 |
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| Order / More Info | Recombinant Zaire ebolavirus (strain Kikwit-95) (ZEBOV) (Zaire Ebola virus) Envelope glycoprotein from MYBIOSOURCE INC. |
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| Product Specific References | The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing.Sanchez A., Trappier S.G., Mahy B.W.J., Peters C.J., Nichol S.T.Proc. Natl. Acad. Sci. U.S.A. 93:3602-3607(1996) |
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