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| Product Name | CD134 Ligand CD8a, Fusion Protein |
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| Description | Purified by affinity chromatography. Human CD134L (OX-40 Ligand) is a type II membrane protein with homology to TNF which is expressed on activated B cells and activated endothelial cells. CD134L binds to CD134 present on activated T cells, providing a costimulatory signal (1). This pathway seems to be more effective for costimulation of CD4+ helper T cells than for CD8+ effector T cells (4). Blockade of this interaction in mouse abrogated immunological effects in several models of immflamation and rejection (5,6,7,8). Functional Application: CD134L-muCD8 fusion protein binds to CD134 positive cells in Flow cytometry. Human CD134L-muCD8 Fusion Protein* Molecular Structure: A soluble molecule consisting of the extracellular domain (132 aa) of human CD134L fused to the extracellular domain (167aa) of murine CD8 alpha. Transfectant Cell Line: CHO Applications: Suitable for use in ELISA, Flow cytometry. |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | ELISA FC |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2515-40F |
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| Order / More Info | CD134 Ligand CD8a, Fusion Protein from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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