| 产品详情 |
| Edit |   |
| Antigenic Specificity | PTBP1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peroxidase (HRP) conjugate |
| Size | n/a |
| Concentration | n/a |
| Applications | ELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PTBP1 Antibody (HRP) LS-C498464. Specificity: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806). |
| Immunogen | Recombinant Human Polypyrimidine tract-binding protein 1 protein (135-292AA) |
| Other Names | PTBP1, HnRNP I, HNRNPI, HNRPI, PTB, PPTB, PTB2, PTB4, RNA-binding protein, HNRNP-I, PTB-1, PTB-T, PTB3 |
| Gene, Accession # | PTBP1, Gene ID: 5725 |
| Catalog # | LS-C498464 |
| Price | |
| Order / More Info | PTBP1 Antibody from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
| 产品资料 |
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