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| Product Name | Recombinant Clostridium tetani Tetanus toxin |
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| Description | 2-457. Partial, provide the Tetanus toxin light chain. MW: 55.42kD. Purity >90% as determined by SDS-PAGE. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrev |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Tentoxylysin] |
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| Gene, Accession, CAS # | tetX, Gene ID: 24255210, Accession: WP_011100836.1 |
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| Catalog # | MBS1262435 |
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| Order / More Info | Recombinant Clostridium tetani Tetanus toxin from MYBIOSOURCE INC. |
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| Product Specific References | Tetanus toxinprimary structure, expression in E. coli, and homology with botulinum toxins.Eisel U., Jarausch W., Goretzki K., Henschen A., Engels J., Weller U., Hudel M., Habermann E., Niemann H.EMBO J. 5:2495-2502(1986) The complete nucleotide sequence of tetanus toxin.Fairweather N.F., Lyness V.A.Nucleic Acids Res. 14:7809-7812(1986) The genome sequence of Clostridium tetani, the causative agent of tetanus disease.Brueggemann H., Baeumer S., Fricke W.F., Wiezer A., Liesegang H., Decker I., Her |
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