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| Product Name | H3F3A, Recombinant, Human, aa2-136, GST-Tag (Histone H3.3) |
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| Description | Purity ~90% (SDS-PAGE). Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacent throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Source: Recombinant protein corresponding to aa2-136 from human H3F3A, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~42.2kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P84243 |
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| Catalog # | 373576 |
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| Order / More Info | H3F3A, Recombinant, Human, aa2-136, GST-Tag (Histone H3.3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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