| 产品详情 |
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| Product Name | BEND6, Recombinant, Human, aa1-279, His-Tag (BEN Domain-Containing Protein 6, C6orf65) |
| Description | Purity ~90% (SDS-PAGE). BEND6, as known as BEN domain-containing protein 6, is a neural BEN-solo factor that shares many functional attributes with Drosophila Insensitive, a co-repressor for the Drosophila CSL factor. This protein binds the mammalian CSL protein CBF1 and antagonizes Notch-dependent target activation. In addition, its association with Notch- and CBF1-regulated enhancers is promoted by CBF1 and antagonized by activated Notch. In utero electroporation experiments showed that ectopic BEND6 inhibited Notch-mediated self-renewal of neocortical neural stem cells and promoted neurogenesis. Source: Recombinant protein corresponding to aa1-279 from human BEND6, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~33.6kD (302aa), confirmed by MALDI-TOF Applications: Suitable for use in SDS-PAGE. |
| Size | 100ug, 500ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | Accession: NP_689944 |
| Catalog # | 217972 |
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| Order / More Info | BEND6, Recombinant, Human, aa1-279, His-Tag (BEN Domain-Containing Protein 6, C6orf65) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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