| 产品详情 |
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| Product Name | Cytostatin (sodium salt) |
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| Description | Purity >75%. Cytostatin is a natural antitumor inhibitor of cell adhesion to extracellular matrix, blocking adhesion of B16 melanoma cells to laminin and collagen type IV in vitro (IC50 s = 1.3 and 1.4 µg/ml, respectively) and B16 cells metastatic activity in mice. It induces apoptosis of FS3 mouse fibrosarcoma cells (IC50 = 3.1 µg/ml). Cytostatin potently and selectively inhibits protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), while having no effect against PP1, PP2B, or PP5. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (5S,6S)-5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-2H-pyran-2-one, monosodium salt |
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| Gene, Accession, CAS # | CAS: 457070-06-3 |
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| Catalog # | LS-H7325 |
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| Price | |
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| Order / More Info | Cytostatin (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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