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| Product Name | uBA3, 1-463aa, Human, His tag, E Coli |
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| Description | MW: 54.4 kDa (487aa). Purity >90% by SDS-PAGE. uBA3, also known as NEDD8-activating enzyme E1 catalytic subunit, is the catalytic subunit of the dimeric uBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-uBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of uBE2M. Recombinant human uBA3 protein, fused to His-tag at N-termi |
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| Size | 0.1 mg, 0.5 mg |
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| Concentration | 1 mg/ml (determined by Bradford assay) |
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| Applications | SDS-PAGE |
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| Other Names | [NEDD8-activating enzyme E1 catalytic subunit; uBE1C] |
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| Gene, Accession, CAS # | uBA3, Gene ID: 9039, Accession: AAH22853 |
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| Catalog # | MBS204534 |
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| Order / More Info | uBA3, 1-463aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
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| Product Specific References | Gong L., et al. (1999) J. Biol. Chem. 274:12036-12042; Bohnsack R.N., et al. (2003) J. Biol. Chem. 278:26823-26830; |
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