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| Product Name | Recombinant Human Progesterone receptor |
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| Description | 4-232. MW: 50.7kD. Purity >90% as determined by SDS-PAGE. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation. Isoform 4: Increases mitochondrial membrane potential and cellular respiration |
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| Size | 0.2 mg, 0.5 mg, 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Nuclear receptor subfamily 3 group C member 3] |
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| Gene, Accession, CAS # | PGR, Gene ID: 5241, Accession: NP_000917.3 |
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| Catalog # | MBS1265262 |
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| Order / More Info | Recombinant Human Progesterone receptor from MYBIOSOURCE INC. |
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| Product Specific References | Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B.Kastner P., Krust A., Turcotte B., Stropp U., Tora L., Gronemeyer H., Chambon P.EMBO J. 9:1603-1614(1990) Complete amino acid sequence of the human progesterone receptor deduced from cloned cDNA.Misrahi M., Atger M., D'Auriol L., Loosfelt H., Meriel C., Fridlansky F., Guiochon-Mantel A., Galibert F., Milgrom E.Biochem. Biophys. Res. Commun. 143:740-748( |
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