| 产品详情 |
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| Product Name | 4-Methylumbelliferyl Palmitate |
| Description | Purity >98%. Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase. 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL). 4-MUP is cleaved by LAL to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. 4-MUP may also be cleaved by other acid lipases. Recent advances allow the assessment of LAL activity in very small blood volumes using 4-MUP. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | hexadecanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester, 4-MU Palmitate, 4-MUP, Palmitoyl 4-Methylumbelliferone |
| Gene, Accession, CAS # | CAS: 17695-48-6 |
| Catalog # | LS-H6138 |
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| Order / More Info | 4-Methylumbelliferyl Palmitate from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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