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| Product Name | Dysbindin, Recombinant, Human, aa1-270, His-Tag (Dystrobrevin-binding protein 1 isoform C) |
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| Description | Purity ~95% (SDS-PAGE). Dysbindin is a ubiquitously expressed protein that binds to alpha- and beta-dystrobrevins, components of the dystrophin-associated protein complex (DPC) in both muscle and nonmuscle cells. Dysbindin has been strongly implicated in schizophrenia (SZ) susceptibility by a series of independent genetic association and gene expression studies. Among its known functions, dysbindin is part of a protein complex, termed the biogenesis of lysosome-related organelles complex 1 (BLOC-1), the molecular components of which might be involved in the regulation of vesicular trafficking and dendrite branching. Dysbindin effects for brain volume and cortical thickness appear driven by different neurobiological processes. Source: Recombinant protein corresponding to aa1-270 of human Dysbindin, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~34.6kD AA |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_898862 |
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| Catalog # | 349869 |
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| Order / More Info | Dysbindin, Recombinant, Human, aa1-270, His-Tag (Dystrobrevin-binding protein 1 isoform C) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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