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| Product Name | Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 |
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| Description | 40-556aa; Partial of Isoform 2. MW: 73.5kD. Purity >90% as determined by SDS-PAGE. Essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compare |
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| Size | 0.05 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli), 1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Glucosaminyl N-deacetylase/N-sulfotransferase 1; NDST-1; N-heparan sulfate sulfotransferase 1; N-HSST 1; [Heparan sulfate]-glucosamine N-sulfotransferase 1; HSNST 1; 2 domains: Heparan sulfate N-deacetylase 1 (EC:3.-.-.-); Heparan sulfate N-sulfotransferase 1 (EC:2.8.2.-)] |
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| Gene, Accession, CAS # | NDST1, Gene ID: 3340, Accession: NP_001287992.1 |
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| Catalog # | MBS966196 |
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| Order / More Info | Recombinant Human Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 from MYBIOSOURCE INC. |
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| Product Specific References | Cloning of the human heparan sulfate-N-deacetylase/N-sulfotransferase gene from the Treacher Collins syndrome candidate region at 5q32-q33.1.Dixon J., Loftus S.K., Gladwin A.J., Scambler P.J., Wasmuth J.J., Dixon M.J.Genomics 26:239-244(1995) Localization of human heparan glucosaminyl N-deacetylase/N-sulphotransferase to the trans-Golgi network.Humphries D.E., Sullivan B.M., Aleixo M.D., Stow J.L.Biochem. J. 325:351-357(1997) Labell T.L., Milewicz D.J., Bonadio J., Edelhoff S., Disteche C.M., By |
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