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| Product Name | Recombinant Human Beta-adrenergic receptor kinase 1 |
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| Description | 2-221aa; Partial. MW: 29.7kD. Purity >90% as determined by SDS-PAGE. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of th. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [G-protein coupled receptor kinase 2] |
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| Gene, Accession, CAS # | ADRBK1, Gene ID: 156, Accession: NP_001610.2 |
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| Catalog # | MBS1265172 |
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| Order / More Info | Recombinant Human Beta-adrenergic receptor kinase 1 from MYBIOSOURCE INC. |
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| Product Specific References | cDNA cloning and chromosomal localization of the human beta-adrenergic receptor kinase.Benovic J.L., Stone W.C., Huebner K., Croce C., Caron M.G., Lefkowitz R.J.FEBS Lett. 283:122-126(1991) High expression of beta-adrenergic receptor kinase in human peripheral blood leukocytes. Isoproterenol and platelet activating factor can induce kinase translocation.Chuang T.T., Sallese M., Ambrosini G., Parruti G., de Blasi A.J. Biol. Chem. 267:6886-6892(1992) Structure of the human gene encoding the beta-a |
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