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| Product Name | Recombinant Mouse Toll-like receptor 7 |
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| Description | 27-348aa; Partial. MW: 64.2kD. Purity >90% as determined by SDS-PAGE. Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [toll-like receptor 7 isoform a; Toll-like receptor 7; toll-like receptor 7; toll-like receptor 7] |
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| Gene, Accession, CAS # | Tlr7, Gene ID: 170743, Accession: NP_001277684.1 |
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| Catalog # | MBS951025 |
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| Order / More Info | Recombinant Mouse Toll-like receptor 7 from MYBIOSOURCE INC. |
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| Product Specific References | Molecular cloning of murine Toll-like receptor 7.Heil F.J., Lipford G.B., Wagner H., Bauer S.M. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA.Diebold S.S., Kaisho T., Hemmi H., Akira S., Reis e Sousa C.Science 303:1529-1531(2004) The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling.Brinkmann M.M., Spooner E., Hoebe K., Beutler B., Ploegh H.L., Kim Y.M.J. Cell Biol. 177:265-275(2007) UNC93B1 delivers nucle |
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