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| Product Name | Dihydrofolate Reductase Inhibitor Screening Kit (Colorimetric) |
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| Description | Background/Introduction: Dihydrofolate Reductase (DHFR; 5,6,7,8-tetrahydrofolate NADP oxidoreductase; EC 1.5.1.3), is a ubiquitous enzyme that is present in all eukaryotic and prokaryotic cells, playing a key role in folate metabolism. Inhibition of DHFR results in reduction of the intracellular level of tetrahydrofolate, inhibition of RNA and DNA synthesis, and cell death. For this reason, DHFR has been a critically important therapeutic target for anti-tumor drugs. Methotrexate (MTX) is the mo |
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| Size | 100 assays |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [dihydrofolate reductase; Dihydrofolate reductase; dihydrofolate reductase; dihydrofolate reductase] |
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| Gene, Accession, CAS # | Dhfr; Dhfr; Dhfr1, Gene ID: 24312, NCBI: NP_569084.1, UniProt: Q920D2 |
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| Catalog # | MBS846604 |
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| Order / More Info | Dihydrofolate Reductase Inhibitor Screening Kit (Colorimetric) from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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