产品详情 |
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Antigenic Specificity | Parvalbumin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | lyophilized |
Applications | ELISA: Assay dependent, Immunocytochemistry: 1:100-1:200, Immunofluorescence: 1:100-1:200, Immunohistochemistry (Paraffin): 1 µg/mL, Immunoprecipitation: 5 µg/mL, Western Blot: 0.1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Parvalbumin Polyclonal Antibody. Parvalbumin (PV) is a calcium binding protein expressed in specific muscle fibers and fast-firing neurons. PV consists of a single, unbranched chain of linked amino acids and belongs to a larger group of EF hand proteins. Studies have demonstrated that parvalbumin acts in the decay of calcium in the contraction/ relaxation cycle of fast twitch muscles. This data has shown a positive correlation between the rate of relaxation and the concentration of parvalbumin. Parvalbumin is also expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. In amyotrophic lateral sclerosis |
Immunogen | n/a |
Other Names | PV |
Gene, Accession # | Entrez: 25269, 5816; Uniprot: P02625, P20472 |
Catalog # | PA1-933 |
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Order / More Info | Parvalbumin Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 18467652, 18568342, 20128844, 20345217, 20578040, 20874807, 21252265, 22412907, 22455364, 24553925, 24565933, 25086318, 25374513, 26601926, 26987052, 27377368, 28344592 |
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