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| Product Name | SH2D1A, Recombinant, Human |
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| Description | Purity ~95% (SDS-PAGE). SH2D1A is an inhibitor of the signaling lymphocyte activation molecule (SLAM) self-association. This protein is expressed at a high level in thymus and lung, with a lower level of expression in spleen and liver. Defects in SH2D1A are a cause of X-linked lymphoproliferative disease (XLPD) also known as Duncan disease. XLPD is characterized by a rare congenital immunodeficiency following Epstein-Barr virus (EBV) infection. Source: Recombinant corresponding to aa1-128 of human SH2D1A protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MDAVAVYHGK ISRETGEKLL LATGLDGSYL LRDSESVPGV YCLCVLYHGY IYTYRVSQTE TGSWSAETAP GVHKRYFRKI KNLISAFQKP DQGIVIPLQY PVEKKSSARS TQGTTGIRED PDVCLKAP Molecular Weight: 16.3kD (148aa) confirmed by MALDI-TOF |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SH2D1A, Recombinant, Human (SH2 Domain-containing Protein 1A, Duncan Disease SH2-protein, Signaling Lymphocytic Activation Molecule-associated Protein, SLAM-associated Protein T-cell Signal Transduction Molecule SAP, DSHP, SAP) |
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| Gene, Accession, CAS # | Accession: NP_002342 |
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| Catalog # | S1013-31E4 |
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| Order / More Info | SH2D1A, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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