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| Antigenic Specificity | CD80 (CD80) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | B7-1 is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. After engagement of T-cell receptor with antigen in association with major histocompatibility complex class II, a second signal mediated through the binding of B7 to CD28 greatly upregulates the production of multiple lymphokines. B7-1 is a costimulatory molecule for the activation of both CD4 + and CD8 + T lymphocytes that prevents the induction of clonal anergy. Thus, the transfer of B7-1 genes into tumor cells can induce protective immunity and lead to tumor rejection of some tumors in model systems of in vivo tumor growth. |
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| Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to residues of human CD80. |
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| Other Names | CD8|Leu2|MAL|p32|B71|Cd28l|Ly-53|Ly53|MIC17|TSA1|B7|B7-1|B7.1|BB1|CD28LG|CD28LG1|LAB7 |
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| Gene, Accession # | Gene ID: 941 |
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| Catalog # | ABIN343682 |
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| Price | |
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| Order / More Info | CD80 (CD80) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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