产品详情 |
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Antigenic Specificity | Myocilin (MYOC) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Myocilin (MYOC), also known as TIGR or GLC1A, is a secreted glycoprotein of the olfactomedin family, originally identified in trabecular meshwork cells after prolonged treatment with glucocorticoids, and, independently, in the retina (PMID: 9176893, 9169133). It may participate in the obstruction of fluid outflow in the trabecular meshwork. Defects in MYOC are the cause of primary open angle glaucoma (POAG) (PMID: 21709622). MYOC has a molecular weight of 55-57 kDa, besides, a 66-kDa form, which could be a result of post-translational modifications, has also been reported in some researches (PMID: 9497363, 12150989). Synonyms: GPOA, JOAG, TIGR, GLC1A, JOAG1, myocilin, |
Immunogen | Recombinant protein of human MYOC |
Other Names | MYOC|MGC136645|zgc:136645|AI957332|GLC1A|TIGR|GPOA|JOAG|JOAG1|myocilin|Tigr |
Gene, Accession # | Gene ID: 4653,17926,81523 |
Catalog # | ABIN1683799 |
Price | |
Order / More Info | Myocilin (MYOC) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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