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| Product Name | CD24, Recombinant, Mouse,Fc |
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| Description | Purity >90% (SDS-PAGE). CD24 is a highly glycosylated protein expressed as glycosyl-phosphatidyl-inositol (GPI) anchored molecule. Widely expressed, mainly on T cells, B cells and is upregulated in numerous types of cancers. It has costimulatory activity for antigen specific T cell responses. Polymorphisms of human CD24 are associated with several autoimmune diseases. Recently a new role as negative regulator of the immune response has been reported. CD24-deficient mice are more sensitive to inflammatory responses. CD24 together with the membrane protein SIGLEC interacts with danger-associated molecular patterns (DAMPs), such as HMGB1, HSP90 or HSP70. CD24/SIGLEC complex may differentially regulate the host response to DAMPs and PAMPs (pathogen-associated molecular patterns). Sequence: Mouse CD24 (aa 27-52) is fused at the C-terminus to the Fc portion of human IgG1. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | CD24, Recombinant, Mouse,Fc (M1/69-J11D Heat Stable Antigen, Nectadrin, Lymphocyte Antigen 52, X62 Heat Stable Antigen (HSA)) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 44654 |
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| Price | |
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| Order / More Info | CD24, Recombinant, Mouse,Fc from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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