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| Product Name | CD160, Recombinant, Mouse, 6-His-Tag |
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| Description | Purity ~95% (SDS-PAGE). CD160 (also Natural killer cell receptor BY55) is a 16kD (predicted) member of the Ig superfamily (1-4). In mouse, it is expressed principally on nonmyeloid hematopoietic cells. These include CD3+ NK1.1 cells, CD8+ TEM and TCM T cells, CD8a+ IELs, NKT cells, CD8-yd TCR T cells, and vascular endothelial cells (1, 5-7). Mouse CD160 has been identified as a 20-21kD GPI-linked glycoprotein (4, 5). It is synthesized as a preproprotein that is 185aa in length. The precursor contains a 27 aa signal sequence, a 133 aa mature molecule that shows one 98 aa V-type Ig-like domain (aa 28-125), and a 25 aa prosegment that is cleaved to generate a GPI-linkage at Ser160. Mouse GPI-linked CD160 is known to be cleaved by phospholipase C, and this generates a 40kD (presumably dimeric) band in SDS-PAGE (5). One alternative splice form for mouse CD160 is reported that appears to show a deletion of aa 137 - 180. This may generate a soluble molecule (5; GenBank Accession # NP_00115696 |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: AAH21596 |
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| Catalog # | C2548-88P |
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| Order / More Info | CD160, Recombinant, Mouse, 6-His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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