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| Product Name | Pro-SAAS, aa245-254, Rat |
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| Description | Purity ~95% (HPLC). ProSAAS is a newly discovered protein with a neuroendocrine distribution generally similar to that of prohormone convertase 1 (PC1), a peptide processing endopeptidase. ProSAAS mRNA is broadly distributed among neurons in brain and other neuroendocrine tissues (pituitary, adrenal, pancreas). Overexpression of ProSAAS in the AtT-20 cells substantially reduces the rate of processing of POMC(endogenous prohormone proopiomelanocortin) [1]. In wild type mouse brain and pituitary, the majority of ProSAAS is processed into smaller peptides including Little SAAS, PEN and big LEN.[2] A few obesity related propeptides have been processed by PC1 and obesity has been observed to be associated with mutations in the human PC1 gene[3].Does proSAAS- derived peptides play a role in the development of obesity Source: aa245-254, Rat Molecular Weight: ~1013.07 |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 302127 |
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| Price | |
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| Order / More Info | Pro-SAAS, aa245-254, Rat from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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