| 产品详情 |
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| Product Name | Recombinant Mouse Bis(5'-adenosyl)-triphosphatase |
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| Description | 2-150aa; Full Length. MW: 21.2kD. Purity >90% as determined by SDS-PAGE. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extrely low activity with ATP. Modulates transcriptional activation by CTNNB1 and thereby contributes to regulate the expression of genes essential for cell proliferation and survival, such as CCND1 and BIRC5. Plays a role in the induction of apoptosis via SRC and AKT1 sig |
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| Size | 0.01 mg (Yeast), 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [AP3A hydrolase; AP3; Aase; Diadenosine 5',5'''-P1,P3-triphosphate hydrolase; Dinucleosidetriphosphatase; Fragile histidine triad protein] |
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| Gene, Accession, CAS # | Fhit, Gene ID: 14198, Accession: NP_001295215.1 |
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| Catalog # | MBS1190465 |
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| Order / More Info | Recombinant Mouse Bis(5'-adenosyl)-triphosphatase from MYBIOSOURCE INC. |
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| Product Specific References | The murine Fhit locus isolation, characterization, and expression in normal and tumor cells.Pekarsky Y., Druck T., Cotticelli M.G., Ohta M., Shou J., Mendrola J., Montgomery J.C., Buchberg A.M., Siracusa L.D., Manenti G., Fong L.Y., Dragani T.A., Croce C.M., Huebner K.Cancer Res. 58:3401-3408(1998) Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans.Pekarsky Y., Campiglio M., Siprashvili Z., Druck T., Sedkov Y., Tillib S., Draganescu A |
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