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| Product Name | F1Aa, Blocking Peptide (FEM1b) |
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| Description | Purified 60-70%. Peptide (DINYQDQIPRTLEE) corresponding to amino acids 609 to 622 of human F1Aa (1). This sequence is identical to the corresponding sequence of mouse FEM1b (2). Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family. A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aa and FEM1b (1,2). F1Aa/FEM1b is the homologue of C. elegans sex determining protein FEM-1 (1,2). FEM-1/F1Aa is cleaved by CED-3 and caspase (3). FEM-1/F1Aa associates with CED-4 and its mammalian homologue Apaf-1 (3). Overexpression of F1Aa induces apoptosis. F1Aa is therefore a novel member of the death receptor associated protein that mediates apoptosis. F1Aa is expressed in a variety of human and mouse tissues (1,2). Applications: Suitable for use in ELISA, Western Blotting. Positive Control: Mouse liver tissue |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | F0001-05P |
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| Order / More Info | F1Aa, Blocking Peptide (FEM1b) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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