| 产品详情 |
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| Product Name | MLN-4924 |
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| Description | MW: 443.53. Purity ≥98% by HPLC. Background: A potent and selective inhibitor of NEDD8 (Neural precursor cell expressed, developmentally down-regulated 8)-activating enzyme (NAE) (IC?? = 4.7 nM) with potential anticancer activity. NAE activates NEDD8, an ubiquitin-like (UBL) protein that modifies cellular targets in a pathway that is parallel to but distinct from the ubiquitin-proteasome pathway (UPP). Supresses the growth of tumor xenografts in mice. |
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| Size | 0.5 mg, 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [(1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentylmethyl sulfamate] |
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| Gene, Accession, CAS # | CAS: 905579-51-3 |
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| Catalog # | MBS841960 |
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| Order / More Info | MLN-4924 from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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