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| Product Name | Recombinant Mouse Growth/differentiation factor 5 |
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| Description | 376-495aa; Full Length. MW: 17.7kD. Purity >90% as determined by SDS-PAGE. Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction. Secon |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Bone morphogenetic protein 14; BMP-14] |
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| Gene, Accession, CAS # | Gdf5, Gene ID: 14563, Accession: NP_032135.2 |
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| Catalog # | MBS718033 |
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| Order / More Info | Recombinant Mouse Growth/differentiation factor 5 from MYBIOSOURCE INC. |
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| Product Specific References | Limb alterations in brachypodism mice due to mutations in a new member of the TGF beta-superfamily.Storm E.E., Huynh T.V., Copeland N.G., Jenkins N.A., Kingsley D.M., Lee S.-J.Nature 368:639-643(1994) Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S., Teague |
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