| 产品详情 |
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| Product Name | Liver-expressed Antimicrobial Peptide 2, Control Peptide (LEAP-2) |
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| Description | Human genome contains numerous genes whose protein products are unknown in terms of structure, interaction partner, expression, and function. From human blood ultrafiltrate, a novel gene-encoded, cysteine-rich, and cationic peptide termed as liver- expressed antimicrobial peptide 2 (LEAP-2) together with several circulating forms of LEAP-2 differing in their amino-terminal length were identified, all containing a core structure with two disulfide bonds formed by cysteine residues in relative 1-3 and 2-4 positions. The largest native LEAP-2 form of 40aa residues is generated from the precursor at a putative cleavage site for a furin-like endoprotease. In contrast to smaller LEAP-2 variants, this peptide exhibited dose-dependent antimicrobial activity against selected microbial model organisms. LEAP2: rat= 75aa; mouse= 76aa; human= 77aa; Human chromosome: 5q31.1. Protein homology between mose, rat and human LEAP2 is 99%. LEAP2 is expressed in liver, blood, urine and kidney. Source: Synth |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L1600-20C |
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| Order / More Info | Liver-expressed Antimicrobial Peptide 2, Control Peptide (LEAP-2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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