| 产品详情 |
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| Product Name | Amifostine |
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| Description | Purity ~99% (NMR). A cell-permeable aminothiophosphate pro-drug that offers selective protection in many normal, but not in tumor, tissues against the toxic side-effects of radiation and cytotoxic drugs. Its cytoprotective activities have been attributed to its free radical scavenging properties of its active thiol metabolite, WR-1065. The critical step in its activation is its interaction with alkaline phosphatase that is differentially distributed in normal and neoplastic cells. A strong inducer of hypoxia-inducible factor-a1 (HIF-a1) and p53. Shown to reduce PARP proteolysis and levels of active caspase-3 in irradiated mouse ovaries. Formula: C5H15N2O3PS·3H2O Molecular Weight: 268.3 Solubility: H2O |
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| Size | 50mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Amifostine (2-(3-Aminopropyl)aminoethyl Phosphorothioate, Trihydrate, S-2-(3-Aminopropylamino)ethyl-O,O-dihydrogen Phosphorothioate, Trihydrate) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217173 |
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| Order / More Info | Amifostine from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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