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| Product Name | ATB-343 |
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| Description | Purity >98%. Hydrogen sulfide (H2 S) is a naturally-occurring gasotransmitter with vasodilator and inflammatory modulating activity. Non-steroidal anti-inflammatory drugs (NSAIDs), such as indomethacin, diclofenac, and ibuprofen, are some of the most commonly used anti-inflammatory drugs available but exhibit significant side effects, particularly gastric damage, when used chronically. ATB-343 is a hybrid molecule of an H2 S donor and the NSAID indomethacin. In rats, ATB-343 does not cause gastric damage or promote leukocyte adherence to vascular endothelium, effects which are observed with indomethacin treatment alone. These results indicate that H2 S-releasing derivatives of NSAIDs may prove to be more effective anti-inflammatory agents than traditional NSAIDs alone. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-4-(3-thioxo-3H-1,2-dithiol-5-yl)phenyl ester-1H-indole-3-acetic acid |
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| Gene, Accession, CAS # | CAS: 1000700-26-4 |
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| Catalog # | LS-H6653 |
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| Order / More Info | ATB-343 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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