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| Product Name | GDF-11, Recombinant, Human (Growth/Differentiation Factor-11, BMP-11) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. Endotoxin: ≤0.1ng/ug of protein (<1EU/ug). GDF-11 is a myostatin-homologous protein that acts as an inhibitor of nerve tissue growth.GDF-11 has been shown to suppress neurogenesis through a myostatin-like pathway, which involves arrest of progenitor cell-cycle in the G1 phase.Similarities between myostatin and GDF-11, which are 90% identical in their amino acid sequence, suggests that the regulatory mechanisms responsible for maintaining proper tissue size during neural and muscular development might be the same.Recombinant human GDF-11 is a 25.0kD disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity. Recombinant human GDF-11 is a 25.0kD disulfide-linked homodimer containing two 109 amino acid polypeptide chains. It is highly homologous to myostatin/GDF-8 sharing 90% amino-acid sequence identity. Biological Activity: The ED50 was de |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143340 |
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| Order / More Info | GDF-11, Recombinant, Human (Growth/Differentiation Factor-11, BMP-11) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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