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| Product Name | GDF-2, Recombinant, Human (Growth/Differentiation Factor-2, BMP-9) |
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| Description | Purity ~95% (SDS-PAGE). GDF-2 belongs to the TGF-beta cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in non-parenchymal cells of the liver, but is also found in other various cells and tissues. GDF-2 can signal through the ALK1 receptor and has been implicated in a number of physiologic events. These include regulation of the hepatic reticulo-endothelial system, glucose homeostasis, and iron homeostasis, as well as the inhibition of angiogenesis. Recombinant human GDF-2 is a disulfide linked homodimeric protein consisting of two 110aa polypeptide chains. Source: Recombinant protein corresponding to human GDF-2, expressed in CHO cells. Molecular Weight: ~24.1kD Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.9ng/ml. Endotoxin: <0.1ng/ug of prote |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Growth/Differentiation Factor-2, BMP-9 |
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| Gene, Accession, CAS # | GDF2, Gene ID: 2658, SwissProt: Q9UK05 |
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| Catalog # | 219790 |
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| Order / More Info | GDF-2, Recombinant, Human (Growth/Differentiation Factor-2, BMP-9) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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