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| Product Name | GDF-2, Recombinant, Human (Growth/Differentiation Factor-2, BMP-9) |
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| Description | Purity ≥95% by SDS-PAGE gel and HPLC analyses. GDF-2 belongs to the TGF-beta cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-2 is expressed mainly in nonparenchymal cells of the liver, but is also found in other various cells and tissues.GDF-2 can signal through the ALK1 receptor and has been implicated in a number of physiologic events.These include regulation of the hepatic reticuloendothelial system, glucose homeostasis, and iron homeostasis, as well as the inhibition of angiogenesis. Recombinant human GDF-2 is a 24.1kD disulfide linked homodimeric protein consisting of two 110 amino acid polypeptide chains. Biological Activity: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 0.5-1.9ng/ml. AA Sequence: SAGAGSHCQK TSLRVNFEDI GWDSWIIAPKE YEAYECKGGC FFPLADDVTPTK HAIVQTLVHL KFPTKVGKAC CVPTKLSPI |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143342 |
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| Order / More Info | GDF-2, Recombinant, Human (Growth/Differentiation Factor-2, BMP-9) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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