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| Product Name | OCH ((2S,3S,4R)-1-O-(alpha-D-Galactopyranosyl)-N-tetracosanoyl-2-amino-1,3,4-nonanetriol)) |
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| Description | Purity ~95%. Truncated analog of alpha-GalCer. iNKT cell glycolipid agonist. Immunosuppressive. Th2 polarizing. Stimulation of NKT with OCH results in release of primarily Th2 cytokine compared to stimulation with alpha-GalCer, which results in release of a mixture of Th1 and Th2 cytokines. Induces stronger interleukin-4 (IL-4) secretion and weaker interferon-gamma (IFN-gamma) secretion than alpha-GalCer both in vitro and in vivo. Inducer of interleukin-10 (IL-10) and suppressor of diabetes. Shown to prevent experimental autoimmune encephalomyelitis (EAE) in mice, an animal model of multiple sclerosis. Has beneficial effects on type I diabetes in NOD mice. Suppressor of collagen-induced arthritis. Might be useful for immunotherapy of transplant rejection. Formula: C39H77NO9 Solubility: DMSO, 100% ethanol (warm) or methanol (warm) Molecular Weight: ~704.0 |
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| Size | 250ug, 1mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 207309 |
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| Order / More Info | OCH ((2S,3S,4R)-1-O-(alpha-D-Galactopyranosyl)-N-tetracosanoyl-2-amino-1,3,4-nonanetriol)) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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