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| Product Name | Integrin alpha 9 beta 1, Recombinant, Mouse (CD29) |
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| Description | Purity ~95% (SDS-PAGE). Integrin alpha 9 beta 1 is one of twelve integrin family adhesion receptors that share the beta 1 (CD29) subunit (13). It is the noncovalent heterodimer of 150kD alpha 9 and 130kD beta 1 type I transmembrane glycoprotein subunits (3). The alpha 9 extracellular domain (ECD) contains an Nterminal betapropeller structure, followed by domains termed thigh, calf1 and calf2 (2). The beta 1 ECD contains a vWFA domain, which interacts with the alpha 9 betapropeller to form a binding domain when the dimer is in the active, extended and open conformation. The 1006 amino acid (aa) mouse alpha 9 extracellular domain (ECD) shares 95% and 89% aa sequence identity with rat and human alpha 9, respectively, while the 708 aa mouse beta 1 ECD shares 98% aa identity with rat and 9394% with human, bovine, porcine, ovine, canine and feline beta 1. Each subunit has a transmembrane sequence and a short cytoplasmic tail which, for alpha 9, contains binding sites for paxillin and |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 145813 |
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| Order / More Info | Integrin alpha 9 beta 1, Recombinant, Mouse (CD29) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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