产品详情 |
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Antigenic Specificity | CD152 (CTLA-4) |
Clone | 14D3 |
Host Species | Mouse |
Reactive Species | human, rhesus monkey |
Isotype | IgG2a, kappa |
Format | allophycocyanin (APC) conjugate |
Size | 100 Tests |
Concentration | n/a |
Applications | Flow Cytometry: 5 µL (0.03 µg)/test |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD152 (CTLA-4) Monoclonal Antibody (14D3), APC, eBioscience™. CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed on mainly CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells), but with higher affinity than CD28. However, in contrast to CD28 which enhances cell function when bound at the same time as the T cell receptor, CTLA4 inhbits the T cell and prevents it from functioning. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Entrez: 1493; Uniprot: P16410 |
Catalog # | 17-1529-42 |
Price | |
Order / More Info | CD152 (CTLA-4) Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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