| 产品详情 |
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| Product Name | CAMLG, 1-189aa, Human, His tag, E Coli |
| Description | MW: 23.2 kDa (212aa), confirmed by MALDI-TOF. Purity >85% by SDS-PAGE. The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This inte |
| Size | 0.1 mg, 0.5 mg |
| Concentration | 0.5 mg/ml (determined by Bradford assay) |
| Applications | SDS-PAGE |
| Other Names | [Calcium signal-modulating cyclophilin ligand; CAML] |
| Gene, Accession, CAS # | CAMLG, Gene ID: 819, Accession: NP_001736 |
| Catalog # | MBS205331 |
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| Order / More Info | CAMLG, 1-189aa, Human, His tag, E Coli from MYBIOSOURCE INC. |
| Product Specific References | Bram RJ., et al. (1996). Genomics 31 (2): 257-60. |
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