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| Product Name | CAMLG, Recombinant, Human, aa1-189, His-Tag (Calcium signal-modulating cyclophilin ligand) |
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| Description | Purity ~85% (SDS-PAGE). The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. CAMLG functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. Source: Recombinant protein corresponding to aa1-189 of human CAMLG, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~23.2kD AA |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001736 |
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| Catalog # | 349748 |
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| Order / More Info | CAMLG, Recombinant, Human, aa1-189, His-Tag (Calcium signal-modulating cyclophilin ligand) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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