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| Product Name | Recombinant Human TNF receptor-associated factor 6 |
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| Description | 1-522. Full length. MW: 75.6kD. Purity >90% as determined by SDS-PAGE. E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation. Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Ses to also play a role in dendritic |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [E3 ubiquitin-protein ligase TRAF6; Interleukin-1 signal transducer; RING finger protein 85] |
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| Gene, Accession, CAS # | TRAF6, Gene ID: 7189, Accession: NP_004611.1 |
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| Catalog # | MBS1426831 |
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| Order / More Info | Recombinant Human TNF receptor-associated factor 6 from MYBIOSOURCE INC. |
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| Product Specific References | TRAF6 is a signal transducer for interleukin-1.Cao Z., Xiong J., Takeuchi M., Kurama T., Goeddel D.V.Nature 383:443-446(1996) SeattleSNPs variation discovery resourceComplete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S., Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., N |
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