| 产品详情 |
| Edit |   |
|---|
| Product Name | c-MER, Recombinant, Human, GST-Tag (c-Mer Proto-oncogene Tyrosine Kinase, MER, MERTK, MGC133349) |
|---|
| Description | Purified (~70-90%). c-MER is a tyrosine kinase and a member of the MER/AXL/TYRO3 receptor kinase family. The c-MER gene encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type domains, and one tyrosine kinase domain. Functional knockout of c-MER in mice shows the mice to have macrophages deficient in the clearance of apoptotic thymocytes thereby demonstrating the critical role for c-MER in the engulfment and efficient clearance of apoptotic cells. Defects in c-MER have been associated with retinitis pigmentosa, a phenotype that can be reversed by replacement of the c-MER gene product. Source: Recombinant protein corresponding to human c-MER, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~58kD Specific Activity: 1231nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Accession: NM_006343, SwissProt: Q12866 |
|---|
| Catalog # | 499833 |
|---|
| Price | |
|---|
| Order / More Info | c-MER, Recombinant, Human, GST-Tag (c-Mer Proto-oncogene Tyrosine Kinase, MER, MERTK, MGC133349) from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|