| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CD366 (TIM3) |
|---|
| Clone | 8B.2C12 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG1, kappa |
|---|
| Format | eFluor 450 conjugate |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Flow Cytometry: 0.25 µg/test |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CD366 (TIM3) Monoclonal Antibody (8B.2C12), eFluor 450, eBioscience™. TIM3 (Hepatitis A virus cellular receptor 2, HAVCR2, T-cell immunoglobulin, mucin-dmain containing-3) is a 281 amino acid long, Type-1 Th1- specific cell surface glycoprotein expressed on terminally differentiated CD4+Th1 and CD8+Tc1 cells. TIM3 consists of an IgV-like domain, a mucin-like domain in the extracellular region, and a conserved Tyrosine phosphorylation motif in the cytoplasmic region. TIM3 is involved in macrophage activation and induction of autoimmune diseases. Further, TIM3 down-regulates aggressive Th1-mediated immune responses and facilitates in the development of immune tolerance. Pathological significance of TIM3 has been attributed to Experiment |
|---|
| Immunogen | n/a |
|---|
| Other Names | HAVCR2,TIM-3 |
|---|
| Gene, Accession # | Entrez: 171285; Uniprot: Q8VIM0 |
|---|
| Catalog # | 48-5871-82 |
|---|
| Price | |
|---|
| Order / More Info | CD366 (TIM3) Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | PubMed: 15905494, 16709797, 22168579, 28345650 |
|---|
| 产品资料 |
|
|